SGSM1 Antikörper (Middle Region)

Produktnummer ABIN1449980

Der Kaninchen Polyklonal Anti-SGSM1-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, SGSM1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SGSM1 Antikörper (Middle Region) (ABIN1449980)

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-SGSM1 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu SGSM1

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Andere Bezeichnung: SGSM1

Hintergrund: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.Synonyms: RUTBC2, Small G protein signaling modulator 1

Molekulargewicht: 126 kDa

Gen-ID: 129049

NCBI Accession: NP_001035037