SGSM1 Antikörper (Middle Region)

Produktnummer ABIN1449980

Der Kaninchen Polyklonal anti-SGSM1 Antikörper wird verwendet zum Nachweis von SGSM1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für SGSM1 Antikörper (Middle Region) (ABIN1449980)

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-SGSM1 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu SGSM1

Target: SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))

Andere Bezeichnung: SGSM1

Hintergrund: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.Synonyms: RUTBC2, Small G protein signaling modulator 1

Molekulargewicht: 126 kDa

Gen-ID: 129049

NCBI Accession: NP_001035037