LNPEP Antikörper (C-Term)

Produktnummer ABIN1449971

Der Kaninchen Polyklonal anti-LNPEP Antikörper wird verwendet zum Nachweis von LNPEP in Proben von Human. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für LNPEP Antikörper (C-Term) (ABIN1449971)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LNPEP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-LNPEP Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid synthetic peptide near the carboxy terminus of Human LNPEP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Andere Bezeichnung: LNPEP

Hintergrund: LNPEP, also known as insulin-responsive aminopeptidase (IRAP), was initially identified as an abundant protein that is associated with specialized endosomes termed GLUT4 storage vesicles (GSVs) in adipocytes. The luminal domain of LNPEP contains an aminopeptidase activity that is involved in peptide hormone processing and antigenic peptide processing. LNPEP is also a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to the GSVs.Synonyms: Cystinyl aminopeptidase, EC=3.4.11.3, IRAP, Insulin-regulated membrane aminopeptidase, Insulin-responsive aminopeptidase, LNPEP, Leucyl-cystinyl aminopeptidase, OTASE, Oxytocinase, P-LAP, Placental leucine aminopeptidase

Molekulargewicht: 113 kDa

Gen-ID: 4012

NCBI Accession: NP_005566

Pathways: Regulation of long-term Neuronal Synaptic Plasticity