CMPK2 Antikörper (C-Term)

Produktnummer ABIN1449968

Der Kaninchen Polyklonal Anti-CMPK2-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, CMPK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CMPK2 Antikörper (C-Term) (ABIN1449968)

Target: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMPK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CMPK2 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the carboxy terminus of Human CMPK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CMPK2

Target: CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))

Andere Bezeichnung: CMPK2

Hintergrund: UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory responseSynonyms: LOC129607, UMP-CMP kinase 2

Molekulargewicht: 49 kDa

Gen-ID: 129607

NCBI Accession: NP_997198

Pathways: Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin