RAB21 Antikörper (C-Term)

Produktnummer ABIN1449947

Der Kaninchen Polyklonal anti-RAB21 Antikörper wird verwendet zum Nachweis von RAB21 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für RAB21 Antikörper (C-Term) (ABIN1449947)

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-RAB21 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the carboxy terminus of Human RAB21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RAB21

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Andere Bezeichnung: RAB21

Hintergrund: RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the α-tail of endocytosed integrin.Synonyms: KIAA0118, Rab-21, Ras-related protein Rab-21

Gen-ID: 23011

NCBI Accession: NP_055814