VAMP7 Antikörper (N-Term)

Produktnummer ABIN1449946

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VAMP7 in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 1 Publikation erwähnt.

Kurzübersicht für VAMP7 Antikörper (N-Term) (ABIN1449946)

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAMP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-VAMP7 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the amino terminus of Human VAMP7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-VAMP7 Antikörper (ABIN1449946)

Peña-Altamira, Polazzi, Giuliani, Beraudi, Massenzio, Mengoni, Poli, Zuccarini, Ciccarelli, Di Iorio, Virgili, Monti, Caciagli: "Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors." in: Neurochemistry international, Vol. 115, pp. 37-49, (2018) (PubMed).

Details zu VAMP7

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Andere Bezeichnung: VAMP-7 / SYBL1

Hintergrund: VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.Synonyms: Synaptobrevin-like protein 1, Tetanus-insensitive VAMP, Ti-VAMP, VAMP7, Vesicle-associated membrane protein 7

Gen-ID: 6845

NCBI Accession: NP_001172112