AFF2 Antikörper (Middle Region)
Kurzübersicht für AFF2 Antikörper (Middle Region) (ABIN1449867)
Target
Alle AFF2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- AMGNCNNGPV TIPQRIHHMA ASHVNITSNV LRGYEHWDMA DKLTRENKEF
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Kreuzreaktivität (Details)
- Species reactivity (expected):Mouse, Rat, Horse, Rabbit, Guinea PigSpecies reactivity (tested):Human
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Aufreinigung
- Purified using peptide immunoaffinity column
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Immunogen
- Synthetic peptide directed towards the middle region of human AFF2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- AFF2 (AF4/FMR2 Family, Member 2 (AFF2))
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Andere Bezeichnung
- AFF2 / FMR2
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Hintergrund
- AFF2 is a RNA-binding protein and might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. Defects in AFF2 are the cause of mental retardation X-linked associated with fragile site FRAXE (MRFRAXE). A form of mild to moderate mental retardation associated with learning difficulties, communication deficits, attention problems, hyperactivity, and autistic behavior. It is associated with a fragile site on chromosome Xq28.Synonyms: AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, Protein Ox19
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Gen-ID
- 2334
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NCBI Accession
- NP_002016
Target
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