AOC2 Antikörper (Middle Region)

Produktnummer ABIN1449831

Dieses Anti-AOC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AOC2 in WB. Geeignet für Human, Maus, Rind (Kuh), Hund, Ratte, Zebrafisch (Danio rerio), Huhn und Xenopus laevis.

Kurzübersicht für AOC2 Antikörper (Middle Region) (ABIN1449831)

Target: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte, Zebrafisch (Danio rerio), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AOC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AOC2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AEDIPNTVTL GNRVGFLLRP YNFFDEDPSI FSPGSVYFEK GQDAGLCSIN

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Bovine, Rabbit, Dog, PigSpecies reactivity (tested):Human.

Aufreinigung: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle region of human AOC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Details zu AOC2

Target: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Andere Bezeichnung: AOC2 / RAO

Hintergrund: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.Synonyms: Amine oxidase copper-containing, Retina-specific copper amine oxidase

Gen-ID: 314

NCBI Accession: NP_033720