Integrin beta 3 Antikörper
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- Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
- Integrin beta 3 (ITGB3)
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Mouse. Not Human (PBCM cells on Flow cytometry).
- Aufreinigung
- Protein G agarose
- Immunogen
- Mouse platelet
- Klon
- 1-55-4
- Isotyp
- IgG2a
- Top Product
- Discover our top product ITGB3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Konservierungsmittel
- Without preservative
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Upon receipt, store (in aliqouts) at -20 °C.
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- Target
- Integrin beta 3 (ITGB3)
- Andere Bezeichnung
- CD61 / ITGB3 (ITGB3 Produkte)
- Hintergrund
- Platelet activation results in a conformational change of the membrane spanning platelet integrin GPIIb/IIIa (aIIbß3, CD41/CD61) enabling the binding of the plasma protein fibrinogen. This binding is primarily reversible, but it enhances platelet activation by outside-in signal causing receptor clustering, platelet secretion, and finally irreversible fibrinogen binding and platelet aggregation.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
- Gen-ID
- 10090
- UniProt
- O54890
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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