PDCD1LG2 Antikörper (Extracellular Domain)

Produktnummer ABIN1449245

Der Ratte Monoklonal anti-PDCD1LG2 Antikörper wird verwendet zum Nachweis von PDCD1LG2 in Proben von Maus. Er wurde validiert für FACS.

Kurzübersicht für PDCD1LG2 Antikörper (Extracellular Domain) (ABIN1449245)

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser PDCD1LG2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 54-1

Produktdetails anti-PDCD1LG2 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody reacts with mouse CD273 antigen

Aufreinigung: Protein A agarose

Immunogen: Recombinant mouse PD-L2 extracellular domain

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu PDCD1LG2

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Andere Bezeichnung: CD273 / PDL2

Hintergrund: Programmed death ligand 2 (PD-L2, also known as CD273/B7-DC), a member of B7 family was identified among a library of genes differentially expressed between DCs and activated m acrophages. PD-L2 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA-4 subfamily. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 + T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. In contrast, at high antigen concentrations, PD-L2-PD-1 interactions reduce cytokine production but do not inhibit T cell proliferation.Synonyms: B7DC, PD-1-ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, Programmed cell death 1 ligand 2, Programmed death ligand 2

Gen-ID: 80380

NCBI Accession: NP_079515

UniProt: Q9BQ51