DLK1 Antikörper (PE)

Produktnummer ABIN1449215

Der Ratte Monoklonal Anti-DLK1-Antikörper wurde für FACS validiert. Er ist geeignet, DLK1 in Proben von Maus zu detektieren.

Kurzübersicht für DLK1 Antikörper (PE) (ABIN1449215)

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser DLK1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 24-11-14

Produktdetails anti-DLK1 Antikörper (PE)

Spezifität: This antibody reacts with Dlk.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse

Aufreinigung: Protein G Agarose Chromatography of hybridoma supernatant

Immunogen: Pref-1-Fc protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mLPBS, 0.09 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C.

Details zu DLK1

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Andere Bezeichnung: DLK1

Hintergrund: Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2

Gen-ID: 13386

NCBI Accession: NP_034182

UniProt: Q09163