Stabilin 2 (STAB2) Antikörper

Produktnummer ABIN1449211

Produktdetails

Target: Stabilin 2 (STAB2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts with FEEL-2.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A agarose

Immunogen: Membrane fraction of FEEL-2 transfectant

Klon: 17

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Antigendetails

Target: Stabilin 2 (STAB2)

Andere Bezeichnung: Stabilin 2 / STAB2 (STAB2 Produkte)

Hintergrund: Advanced Glycation End Products (AGEs) are nonenzymatically glycosylated proteins and lipids that accumulate in vascular tissues in aging and diabetes. FEEL-1 (fasciclin, epidermal growth factor (EGF)-like, laminin-type EGF-like, and link domain-containing scavenger receptor-1) and FEEL-2 are an approximately 280 kDa protein that serves as an endocytic receptor for AGEs. FEEL-2 is a paralogous gene of FEEL-1 whose amino acid sequence is about 40 % identical to FEEL-1. Quantitative PCR analyses showed that both FEEL-1 and FEEL-2 are expressed in the spleen and lymph node and liver.Synonyms: EGF-like, FEEL-2, FEEL2, FELL, FEX2, Fasciclin, HARE, Stabilin-2, laminin-type EGF-like and link domain-containing scavenger receptor 2

Molekulargewicht: 280 kDa

Gen-ID: 55576

NCBI Accession: NP_060034

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process