P-Selectin Antikörper (APC)

Produktnummer ABIN1449147

Der APC-konjugierte Maus Monoklonal anti-P-Selectin Antikörper (Klon AK4) (ABIN1449147) detektiert spezifisch P-Selectin in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Primate.

Kurzübersicht für P-Selectin Antikörper (APC) (ABIN1449147)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser P-Selectin Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: AK4

Produktdetails anti-P-Selectin Antikörper (APC)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Primates

Immunogen: Human platelets

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline (PBS), 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE! This products is photosensitive and should be protected from light.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C.

Details zu P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Andere Bezeichnung: CD62P / P-Selectin

Hintergrund: CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

Gen-ID: 6403

NCBI Accession: NP_002996

UniProt: P16109