CD8 Antikörper

Produktnummer ABIN1449140

Es sind 8+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-CD8 Antikörper wird verwendet zum Nachweis von CD8 in Proben von Schaf, Rind (Kuh) und Ziege. Er wurde validiert für FACS, IF, IHC (fro), IP und IHC (p).

Kurzübersicht für CD8 Antikörper (ABIN1449140)

Target: CD8

Reaktivität: Schaf, Rind (Kuh), Ziege

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CC63

Produktdetails anti-CD8 Antikörper

Aufreinigung: Affinity Chromatography on Protein G

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Referenzen für anti-CD8 Antikörper (ABIN1449140)

Lynch, Earley, McGee, Doyle: "Effect of abrupt weaning at housing on leukocyte distribution, functional activity of neutrophils, and acute phase protein response of beef calves." in: BMC veterinary research, Vol. 6, pp. 39, (2010) (PubMed).

Coad, Clifford, Rhodes, Hewinson, Vordermeier, Whelan: "Repeat tuberculin skin testing leads to desensitisation in naturally infected tuberculous cattle which is associated with elevated interleukin-10 and decreased interleukin-1 beta responses." in: Veterinary research, Vol. 41, Issue 2, pp. 14, (2009) (PubMed).

Sidders, Pirson, Hogarth, Hewinson, Stoker, Vordermeier, Ewer: "Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex." in: Infection and immunity, Vol. 76, Issue 9, pp. 3932-9, (2008) (PubMed).

Fulton, Portella, Radke: "Dissemination of bovine leukemia virus-infected cells from a newly infected sheep lymph node." in: Journal of virology, Vol. 80, Issue 16, pp. 7873-84, (2006) (PubMed).

Harris, Werling, Koss, Monaghan, Taylor, Howard: "Expression of caveolin by bovine lymphocytes and antigen-presenting cells." in: Immunology, Vol. 105, Issue 2, pp. 190-5, (2002) (PubMed).

Twizere, Kerkhofs, Burny, Portetelle, Kettmann, Willems: "Discordance between bovine leukemia virus tax immortalization in vitro and oncogenicity in vivo." in: Journal of virology, Vol. 74, Issue 21, pp. 9895-902, (2000) (PubMed).

Winkler, Doster, Jones: "Persistence and reactivation of bovine herpesvirus 1 in the tonsils of latently infected calves." in: Journal of virology, Vol. 74, Issue 11, pp. 5337-46, (2000) (PubMed).

Gross, Callas, Allison: "Identification and distribution of the costimulatory receptor CD28 in the mouse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 2, pp. 380-8, (1992) (PubMed).

Details zu CD8

Target: CD8

Andere Bezeichnung: CD8

Hintergrund: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2