PDIA3 Antikörper (C-Term)

Produktnummer ABIN1440039

Es gibt 1 Publikation für dieses Produkt. Der Ziege Polyklonal anti-PDIA3 Antikörper wird verwendet zum Nachweis von PDIA3 in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Affe, Rind (Kuh), Kaninchen, Schwein, Hamster, Pferd, Ziege, Schaf, Avian, Cat, Huhn und Esel. Er wurde validiert für WB, IF, IHC (p) und IHC (fro).

Kurzübersicht für PDIA3 Antikörper (C-Term) (ABIN1440039)

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Affe, Rind (Kuh), Kaninchen, Schwein, Hamster, Pferd, Ziege, Schaf, Avian, Cat, Huhn, Esel

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PDIA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PDIA3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-ERP57

Sequenz: STAGEIPVVA IRTAKGEKFV MQEEFSRDGK ALERFLQDYF DGNLKRYLKS EPIPESNDGP VKVVVAENFD EIVNNENKDV LIEFYAPWCG HCKNLEPKYK ELGEKLSKDP NIVIAKMDAT ANDVPSPYEV RGFPTIYFSP ANKKLNPKKY EGGRESDFIS YLQREATNPP VIQEEKPKKK KKAQEDL

Spezifität: Detects a band of 60 kDa by Western blot in the following canine, human, monkey, mouse, rat whole cell lysates.

Produktmerkmale: PDIA3 protein disulfide isomerase family A, member 3

Aufreinigung: Epitope affinity purified

Immunogen: Purified recombinante peptide derived from within residues 300 aa to the C-terminus of human ERP57 produced in E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:2,000, IF:1:50-1:500, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody solution should be gently mixed before use.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Referenzen für anti-PDIA3 Antikörper (ABIN1440039)

Alenquer, Vale-Costa, Etibor, Ferreira, Sousa, Amorim: "Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites." in: Nature communications, Vol. 10, Issue 1, pp. 1629, (2019) (PubMed).

Details zu PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Andere Bezeichnung: ERP57

Hintergrund:

Goat polyclonal to ERp57 - endoplasmic reticulum lumen marker. This endoplasmic reticulum protein interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. It has disulfide isomerase activity and complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

58 kDa glucose regulated protein, 58 kDa microsomal protein, disulfide isomerase ER 60, endoplasmic reticulum resident protein 57, endoplasmic reticulum resident protein 60, ER protein 57, ER protein 60, ER protein 61, ERP57, ERp60, ERp61, glucose regulated protein 58 Kd, GRP57, GRP58, HsT17083, P58, PDIA3, phospholipase C alpha, PI PLC, protein disulfide isomerase A3 antibody.

Molekulargewicht: 58 kDa,58 kDa

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis