CDH1
Reaktivität: Human
WB, IHC, FACS, IF, StM, ISt
Wirt: Kaninchen
Monoclonal
CDH1-2208R
unconjugated
Recombinant Antibody
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
2 mg/mL
Buffer
Polyclonal antibody supplied as a 200 µL (2 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide
Handhabung
The antibody solution should be gently mixed before use.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.
Rapino, Castellucci, Lizzi, Sabatucci, Angelucci, Tortolani, Rossi, DAndrea, Maccarrone: "Modulation of Endocannabinoid-Binding Receptors in Human Neuroblastoma Cells by Tunicamycin." in: Molecules (Basel, Switzerland), Vol. 24, Issue 7, (2019) (PubMed).
Canciello, Russo, Berardinelli, Bernabò, Muttini, Mattioli, Barboni: "Progesterone prevents epithelial-mesenchymal transition of ovine amniotic epithelial cells and enhances their immunomodulatory properties." in: Scientific reports, Vol. 7, Issue 1, pp. 3761, (2018) (PubMed).
Target
E-cadherin (CDH1)
(Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
CDH1 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one trans membrane domain, and a and a highly conserved intracellular domain that binds b-catenin and p120-catenin. CDH1 is involved in mechanisms regulating proliferation, mobility and cell-cell adhesions of epithelial cells. Loss of E-cadherin function or expression has been implicated in cancer metastasis and progression. Synonyms: ARC-1, CAM 120/80, CD324, CDH1, cdhc-A, CDHE, ECAD, E-Cad E-cadherin, Epithelial cadherin, l-cam, LCAM, P09803, P12830 / Q9R0T4, UVO, Uvomorulin, XBcad, XB-cadherin, XTCAD-1 antibody. Ensembl identifier: ENSG00000039068