IFI35 Antikörper (PE)

Produktnummer ABIN1437237

Dieser Anti-IFI35 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von IFI35 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für IFI35 Antikörper (PE) (ABIN1437237)

Target: IFI35 (Interferon-Induced Protein 35 (IFI35))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFI35 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB)

Produktdetails anti-IFI35 Antikörper (PE)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFI35

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IFI35

Target: IFI35 (Interferon-Induced Protein 35 (IFI35))

Andere Bezeichnung: IFI35

Hintergrund:

Synonyms: I 35, i-35, I35, P 35, P35, IN35, IN35_HUMAN, Interferon induced 35 kDa protein, Interferon-induced 35 kDa protein.

Background: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events.

Gen-ID: 3430