LMBR1 Antikörper (PE)

Produktnummer ABIN1436612

Der Kaninchen Polyklonal Anti-LMBR1-Antikörper wurde für WB validiert. Er ist geeignet, LMBR1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Schwein zu detektieren.

Kurzübersicht für LMBR1 Antikörper (PE) (ABIN1436612)

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMBR1 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB)

Produktdetails anti-LMBR1 Antikörper (PE)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LMBR1/DIF14

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu LMBR1

Target: LMBR1 (Limb Region 1 Homolog (LMBR1))

Andere Bezeichnung: DIF14

Hintergrund:

Synonyms: ACHP, C7orf2, D 14, D14, Dferentiation related gene 14, Dferentiation related gene 14 protein, Dferentiation-related gene 14 protein, FLJ11665, Limb region 1 homolog mouse, Limb region 1 homolog, Limb region 1 protein, Limb region 1 protein homolog, LMBR 1, LMBR1, LMBR1_HUMAN, PPD 2, PPD2, TPT.

Background: LMBR1 is a 490 amino acid multi-pass membrane protein that is widely expressed with strongest expression in heart and pancreas. Belonging to the LIMR family, LMBR1 shares 95 % sequence identity with the mouse protein and may play crucial role in the evolution of limb and skeletal system. LMBR1 is critical for expression of sonic hedgehog (Shh) in the developing posterior limb bud mesenchyme. Mutations in the gene encoding LMBR1 is the cause of several rare conditions such as acheiropody (ACHP) and syndactyly type 4 (SDYT4). ACHP is an autosomal recessive inherited disorder characterized by bilateral congenital amputations of the hands and feet. LMBR1L (limb region 1 protein homolog-like), also known as LIMR (Lipocalin-1-interacting membrane receptor), is a 489 amino acid multi-pass membrane protein that is thought to act as a receptor for Lipocalin-1 and may also assist in its endocytosis.

Molekulargewicht: 55kDa

Gen-ID: 64327