NLRX1 Antikörper (PE)

Produktnummer ABIN1433302

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NLRX1 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Hund, Rind (Kuh) und Schwein.

Kurzübersicht für NLRX1 Antikörper (PE) (ABIN1433302)

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRX1 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB)

Produktdetails anti-NLRX1 Antikörper (PE)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLR family member X1

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Andere Bezeichnung: NLRX1

Hintergrund:

Synonyms: NOD5, NOD9, NOD26, DLNB26, CLR11.3, NLR family member X1, Caterpiller protein 11.3, Nucleotide-binding oligomerization domain protein 26, Nucleotide-binding oligomerization domain protein 5, Nucleotide-binding oligomerization domain protein 9, NLRX1

Background: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).

Molekulargewicht: 108kDa

Gen-ID: 79671

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interaktom