GRID1 Antikörper (PE-Cy5)

Produktnummer ABIN1429702

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRID1 in FACS. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Huhn, Rind (Kuh) und Hund.

Kurzübersicht für GRID1 Antikörper (PE-Cy5) (ABIN1429702)

Target: GRID1 (Glutamate Receptor, Ionotropic, delta 1 (GRID1))

Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRID1 Antikörper ist konjugiert mit PE-Cy5

Applikation: Flow Cytometry (FACS)

Produktdetails anti-GRID1 Antikörper (PE-Cy5)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRID1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GRID1

Target: GRID1 (Glutamate Receptor, Ionotropic, delta 1 (GRID1))

Andere Bezeichnung: GRID1

Hintergrund:

Synonyms: GluR delta 1, GluR delta 1 subunit, GluR delta-1 subunit, Glutamate receptor delta 1 subunit, Glutamate receptor delta-1 subunit, Glutamate receptor ionotropic delta 1, GRID 1, Grid1, GluD1, GRID1_HUMAN, KIAA1220.

Background: Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are divided into two categories, namely NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors consist of seven structurally related subunits, designated GluR-1 to -7, and are primarily responsible for fast excitatory neurotransmissions carried out by glutamate. GluR-delta 1 (Glutamate receptor delta-1 subunit), also known as GRID1, is a multi-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain. Localized to the cell junction and the postsynaptic cell membrane, GluR-delta 1 functions as a glutamate receptor that regulates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity. Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, a chronic and severe brain disorder.

Molekulargewicht: 110kDa

Gen-ID: 2894

UniProt: Q9ULK0