GABRQ Antikörper (PE)

Produktnummer ABIN1429640

Der Kaninchen Polyklonal Anti-GABRQ-Antikörper wurde für FACS validiert. Er ist geeignet, GABRQ in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GABRQ Antikörper (PE) (ABIN1429640)

Target: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRQ Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-GABRQ Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRQ/GABA A Receptor ta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100)

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu GABRQ

Target: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Andere Bezeichnung: Gabrq/Gaba A Receptor theta

Hintergrund:

Gamma-aminobutyric acid type A (GABAA) receptors mediate inhibitory neurotransmission in the mammalian central nervous system. The receptor exists as a pentameric ion channel composed by heteromeric combinations of alpha, beta, gamma, delta, epsilon, theta, or pi subunits. Only specific subunit combinations produce viable receptors, while others never translocate to the cell surface from the ER where they are synthesized, and subsequently degraded. The theta subunit forms a receptor in combination with alpha3 subunits in monoaminergic cell groups. These receptors, found especially in the septum, preoptic areas, hypothalamic nuclei, amygdala and thalamus, likely have unique pharmacological properties linked to their expression in this particular cell type and not cholinergic cell groups, and may play a role in opiate withdrawl symptoms.

Subcellular location: Extracellular

Synonyms: gamma aminobutyric acid GABA receptor, theta, Gamma aminobutyric acid receptor theta subunit precursor, gamma aminobutyric acid receptor, theta, THETA, GBRT_HUMAN.