GABRG3 Antikörper (PE-Cy5)

Produktnummer ABIN1429627

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GABRG3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für GABRG3 Antikörper (PE-Cy5) (ABIN1429627)

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRG3 Antikörper ist konjugiert mit PE-Cy5

Applikation: Western Blotting (WB)

Produktdetails anti-GABRG3 Antikörper (PE-Cy5)

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRG3/GABA A Receptor gamma 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GABRG3

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Andere Bezeichnung: GABRG3/GABA A Receptor gamma 3

Hintergrund:

Synonyms: GABAA receptor, GABAA receptor subunit gamma 3, GABR G3, GABRG 3, GABRG3, Gamma aminobutyric acid GABA A receptor gamma 3, Gamma aminobutyric acid A receptor gamma 3, Gamma aminobutyric acid receptor subunit gamma 3, GBRG3_HUMAN.

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R Alpha 1-6, GABAA R Beta 1-3, GABAA R Gamma 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Zeta 1 and GABAA R Zeta 2. The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Molekulargewicht: 52kDa