P2RY10 Antikörper (PE-Cy5)

Produktnummer ABIN1429577

Der Kaninchen Polyklonal Anti-P2RY10-Antikörper wurde für WB und FACS validiert. Er ist geeignet, P2RY10 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für P2RY10 Antikörper (PE-Cy5) (ABIN1429577)

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P2RY10 Antikörper ist konjugiert mit PE-Cy5

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-P2RY10 Antikörper (PE-Cy5)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P2Y10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu P2RY10

Target: P2RY10 (Purinergic Receptor P2Y, G-Protein Coupled, 10 (P2RY10))

Andere Bezeichnung: P2Y10

Hintergrund:

Synonyms: G protein coupled purinergic receptor P2Y10, P2ry10, P2Y like receptor, P2Y purinoceptor 10, P2Y-like receptor, P2Y10, P2Y10_HUMAN, Purinergic receptor P2Y G protein coupled 10, Putative P2Y purinoceptor 10.

Background: Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.

Molekulargewicht: 39kDa

Gen-ID: 27334

UniProt: O00398