GABRA6 Antikörper (PE-Cy7)

Produktnummer ABIN1429544

Der Kaninchen Polyklonal Anti-GABRA6-Antikörper wurde für WB validiert. Er ist geeignet, GABRA6 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund und Schwein zu detektieren.

Kurzübersicht für GABRA6 Antikörper (PE-Cy7) (ABIN1429544)

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRA6 Antikörper ist konjugiert mit PE-Cy7

Applikation: Western Blotting (WB)

Produktdetails anti-GABRA6 Antikörper (PE-Cy7)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GABRA6

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Andere Bezeichnung: GABRA6/GABA A Receptor alpha 6

Hintergrund:

Synonyms: GABA A, GABA A Receptor alpha 6 polypeptide, GABA A receptor alpha 6, GABA A receptor subunit alpha 6, GABA subunit A receptor alpha 6, GABAA receptor subunit alpha-6, GABRA 6, GABRA6, Gamma aminobutyric acid A receptor alpha 6, Gamma aminobutyric acid GABA A receptor alpha 6, Gamma aminobutyric acid receptor subunit alpha 6, Gamma-aminobutyric acid receptor subunit alpha-6, GBRA6_HUMAN, MGC116903, MGC116904.

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R gamma 1-3, GABAA R gamma , GABAA R delta. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Molekulargewicht: 49kDa

Gen-ID: 2559

UniProt: Q16445

Pathways: Synaptic Membrane