GABRA6 Antikörper (PE)

Produktnummer ABIN1429540

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GABRA6 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für GABRA6 Antikörper (PE) (ABIN1429540)

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRA6 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB)

Produktdetails anti-GABRA6 Antikörper (PE)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GABRA6

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Andere Bezeichnung: Gabra6/Gaba A Receptor alpha 6

Hintergrund:

Synonyms: GABA A, GABA A Receptor alpha 6 polypeptide, GABA A receptor alpha 6, GABA A receptor subunit alpha 6, GABA subunit A receptor alpha 6, GABAA receptor subunit alpha-6, GABRA 6, GABRA6, Gamma aminobutyric acid A receptor alpha 6, Gamma aminobutyric acid GABA A receptor alpha 6, Gamma aminobutyric acid receptor subunit alpha 6, Gamma-aminobutyric acid receptor subunit alpha-6, GBRA6_HUMAN, MGC116903, MGC116904.

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R gamma 1-3, GABAA R gamma , GABAA R delta. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Gen-ID: 2559

UniProt: Q16445

Pathways: Synaptic Membrane