ADRA2C Antikörper (PE-Cy7)

Produktnummer ABIN1429439

Der Kaninchen Polyklonal Anti-ADRA2C-Antikörper wurde für FACS validiert. Er ist geeignet, ADRA2C in Proben von Human, Maus, Ratte, Schwein und Hund zu detektieren.

Kurzübersicht für ADRA2C Antikörper (PE-Cy7) (ABIN1429439)

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Reaktivität: Human, Maus, Ratte, Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2C Antikörper ist konjugiert mit PE-Cy7

Applikation: Flow Cytometry (FACS)

Produktdetails anti-ADRA2C Antikörper (PE-Cy7)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADRA2C/alpha 2C Adrenergic Receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ADRA2C

Target: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Andere Bezeichnung: ADRA2C/alpha 2C Adrenergic Receptor

Hintergrund:

Synonyms: Adra 2c, Adra 2c, ADRA2C, ADRA2C, ADRA2L2, ADRA2L2, ADRA2RL2, ADRA2RL2, ADRARL2, ADRARL2, Adrenergic alpha 2C receptor, Adrenoceptor alpha 2C, Alpha 2C adrenergic receptor, Alpha 2C adrenergic receptor subtype C4, Alpha 2C adrenoceptor, Alpha 2C adrenoreceptor, Alpha 2CAR, alpha2 AR C4, alpha2 AR C4, alpha2 C4, alpha2 C4, alpha2C, alpha2C, ALPHA2CAR, alpha2cii-adrenergic receptor, Subtype alpha2 C4, Subtype alpha2 C4, ADA2C_HUMAN.

Background: alpha2C-adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson?s disease, panic disorders, and Huntington disease (HD) progression. A genetic variant in the alpha2C-AR coding region (Del322-325) renders the receptor partially uncoupled from Gi, and is a contributing risk factor for heart failure. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.

Molekulargewicht: 49kDa

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process