SLITRK4 Antikörper (PE)

Produktnummer ABIN1429020

Dieses Anti-SLITRK4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SLITRK4 in FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SLITRK4 Antikörper (PE) (ABIN1429020)

Target: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLITRK4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SLITRK4 Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLITRK4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100)

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu SLITRK4

Target: SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))

Andere Bezeichnung: Slitrk4

Hintergrund:

SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK4 (SLIT and NTRK-like protein 4) is a 837 amino acid single-pass type I membrane protein that contains 18 LRR (leucine-rich) repeats and is expressed in neural tissues, specifically in the thalamus, hypothalamus, subventricular zone, CA3 region of the hippocampus and cortical plate. SLITRK4 may be upregulated in some astrocytic brain tumors such as glioblastomas, astrocytomas and primitive neuroectodermal tumors. As compared with its family member SLITRK2, SLITRK4 only weakly suppresses neurite outgrowth. A study using genome-wide transcriptional profiling suggested that the gene encoding SLITRK4, as well as the ARL5B and PLA2G7 genes, may be involved in the pathogenesis of preeclampsia.

Subcellular location: Extracellular

Synonyms: DKFZp547M2010, SLIK4_HUMAN, SLIT and NTRK like family member 4, SLIT and NTRK like protein 4, SLIT and NTRK-like protein 4, Slit and trk like 4 protein, Slit and trk like gene 4, SLITRK 4, SLITRK4.