ATP13A2 Antikörper (PE)

Produktnummer ABIN1427815

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATP13A2 in . Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für ATP13A2 Antikörper (PE) (ABIN1427815)

Target: ATP13A2 (ATPase Type 13A2 (ATP13A2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP13A2 Antikörper ist konjugiert mit PE

Applikation: Bitte anfragen

Produktdetails anti-ATP13A2 Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP13A2

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu ATP13A2

Target: ATP13A2 (ATPase Type 13A2 (ATP13A2))

Andere Bezeichnung: Park9/Atp13a2

Hintergrund:

ATP13A2 is a 1,180 amino acid multi-pass membrane protein that belongs to the P5 subfamily of ATPases which play an important role in the transportation of inorganic cations. Expressed as multiple alternative spliced isoforms, ATP13A2 functions to catalyze the conversion of ATP to ADP and a free phosphate, thereby participating in the active transport of ions across cellular membranes. Defects in the gene encoding ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS), a rare hereditary type of Parkinson’s disease that exhibits juvenile onset and is characterized by neurodegeneration and dementia. The ATP13A2 gene maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.

Subcellular location: Extracellular

Synonyms: AT132_HUMAN, Atp13a2, ATPase type 13A2, CLN12, HSA9947, KRPPD, PARK9, Probable cation transporting ATPase 13A2, Probable cation-transporting ATPase 13A2, Putative ATPase, RP1-37C10.4.

Pathways: Ribonucleoside Biosynthetic Process