ATRNL1 Antikörper (PE)

Produktnummer ABIN1426805

Produktdetails anti-ATRNL1 Antikörper (PE)

Target: ATRNL1 (Attractin-Like 1 (ATRNL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATRNL1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATRNL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100)

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu ATRNL1

Target: ATRNL1 (Attractin-Like 1 (ATRNL1))

Andere Bezeichnung: Atrnl1 (ATRNL1 Produkte)

Hintergrund:

ATRNL1 is a 1,379 amino acid single-pass type I membrane protein that may play a role in melanocortin signaling pathways that regulate energy homeostasis. The ATRNL1 protein contains a C-type lectin domain, a CUB domain, two EGF-like domains, six Kelch repeats, two laminin EGF-like domains and five PSI domains. ATRNL1 interacts with MC4-R in several regions known to be important in the regulation of energy homeostasis by melanocortins, such as the paraventricular nucleus of hypothalamus and the dorsal motor nucleus of the vagus. The ATRNL1 gene is conserved in dog, cow, mouse, rat, chicken, zebrafish and C. elegans, exists as two alternatively spliced isoforms and maps to human chromosome 10q25.3. Strong evidence of linkage to late-onset Alzheimer disease (LOAD) is linked to chromosome 10, which implicates a wide region and at least one disease-susceptibility locus.

Subcellular location: Extracellular

Synonyms: ATRN1_HUMAN, ATRNL1, Attractin-like protein 1, KIAA0534.