Calsyntenin 2 Antikörper (PE)

Produktnummer ABIN1425995

Produktdetails anti-Calsyntenin 2 Antikörper (PE)

Target: Calsyntenin 2 (CLSTN2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calsyntenin 2 Antikörper ist konjugiert mit PE

Applikation: Bitte anfragen

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLSTN2

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu Calsyntenin 2

Target: Calsyntenin 2 (CLSTN2)

Andere Bezeichnung: Clstn2 (CLSTN2 Produkte)

Hintergrund:

Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.

Subcellular location: Extracellular

Synonyms: Alc, Alcadein, Alcadein Gamma, Alcagamma, Alzheimer's disease related cadherin like protein, Calsyntenin 2, CLSTN 2, CS 2, CS2, FLJ39113, FLJ39499, MGC119560, CSTN2_HUMAN.