PCDHb4 Antikörper (PE)

Produktnummer ABIN1425005

Der Kaninchen Polyklonal Anti-PCDHb4-Antikörper wurde für validiert. Er ist geeignet, PCDHb4 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PCDHb4 Antikörper (PE) (ABIN1425005)

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHb4 Antikörper ist konjugiert mit PE

Applikation: Bitte anfragen

Produktdetails anti-PCDHb4 Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB4

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu PCDHb4

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Andere Bezeichnung: Pcdhb4

Hintergrund:

Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB4 (Protocadherin beta-4) is a 795 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB4) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB4 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain.

Subcellular location: Extracellular

Synonyms: PCDB4_HUMAN, PCDH beta4, PCDH-beta-4, PCDHB4, PCDHB 4, PCDHB-4, Pcdhb5A, PcdhbD, Protocadherin beta-4.