Neuroligin 2 Antikörper (PE-Cy5)

Produktnummer ABIN1424807

Der Kaninchen Polyklonal Anti-Neuroligin 2-Antikörper wurde für FACS validiert. Er ist geeignet, Neuroligin 2 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Schwein und Kaninchen zu detektieren.

Kurzübersicht für Neuroligin 2 Antikörper (PE-Cy5) (ABIN1424807)

Target: Neuroligin 2 (NLGN2)

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuroligin 2 Antikörper ist konjugiert mit PE-Cy5

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Neuroligin 2 Antikörper (PE-Cy5)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLGN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Details zu Neuroligin 2

Target: Neuroligin 2 (NLGN2)

Andere Bezeichnung: NLGN2

Hintergrund:

Synonyms: NL1, NL2, Neuroligin 1, Neuroligin 2, Neuroligin I, Ortholog of human and rat neuroligin 2 NLGN2, NLGN2_HUMAN.

Background: Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.

Molekulargewicht: 90kDa

Gen-ID: 57555

Pathways: Cell-Cell Junction Organization, Synaptic Membrane