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DGCR6L Antikörper (Cy3)

This anti-DGCR6L antibody (ABIN1423679) is a Rabbit Polyclonal antibody detecting DGCR6L in WB, IF (p). Suitable for Human, Mouse, Rat.
Produktnummer ABIN1423679

Quick Overview for DGCR6L Antikörper (Cy3) (ABIN1423679)

Target

Alle DGCR6L Antikörper anzeigen
DGCR6L (DiGeorge Syndrome Critical Region Gene 6-Like (DGCR6L))

Reaktivität

  • 42
  • 17
  • 16
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 41
  • 1
Kaninchen

Klonalität

  • 42
Polyklonal

Konjugat

  • 14
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DGCR6L Antikörper ist konjugiert mit Cy3

Applikation

  • 32
  • 14
  • 12
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DGCR6L

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    DGCR6L (DiGeorge Syndrome Critical Region Gene 6-Like (DGCR6L))

    Andere Bezeichnung

    DGCR6L

    Hintergrund

    Synonyms: DGC6L_HUMAN, DGCR6L, DiGeorge syndrome critical region 6-like protein, Protein DGCR6L.

    Background: Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin-1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome, a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt?s lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.

    Gen-ID

    85359
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