CPQ Antikörper (Cy5)

Produktnummer ABIN1423296

Dieses Anti-CPQ-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CPQ in WB und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für CPQ Antikörper (Cy5) (ABIN1423296)

Target: CPQ (Carboxypeptidase Q (CPQ))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPQ Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CPQ Antikörper (Cy5)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PGCP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CPQ

Target: CPQ (Carboxypeptidase Q (CPQ))

Andere Bezeichnung: PGCP

Hintergrund:

Synonyms: Plasma glutamate carboxypeptidase, CBPQ_HUMAN.

Background: PGCP is a 472 amino acid secreted protein that is primarily detected in blood plasma. PGCP is a carboxypeptidase that potentially is involved in the hydrolysis of circulating peptides. Due to its upregulation in hepatocellular carcinoma (HCC), it is suspected that PGCP may be a potential serological marker for HCC. PGCP is a member of the Peptidase M28 family of proteins, which also includes PSM (prostate-specific membrane antigen), metallopeptidases and aminopeptidases. The gene encoding PGCP maps to chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis.In humans, PGCP is found principally in blood plasma. It is a Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides.

Gen-ID: 10404