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C17orf75 Antikörper (AA 210-260) (HRP)

This anti-C17orf75 antibody (ABIN1421722) is a Rabbit Polyclonal antibody detecting C17orf75 in WB, IHC (p). Suitable for Human, Rat, Mouse.
Produktnummer ABIN1421722

Kurzübersicht für C17orf75 Antikörper (AA 210-260) (HRP) (ABIN1421722)

Target

Alle C17orf75 Antikörper anzeigen
C17orf75 (Chromosome 17 Open Reading Frame 75 (C17orf75))

Reaktivität

  • 33
  • 18
  • 17
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 30
  • 3
Kaninchen

Klonalität

  • 30
  • 3
Polyklonal

Konjugat

  • 16
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser C17orf75 Antikörper ist konjugiert mit HRP

Applikation

  • 28
  • 13
  • 8
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 210-260

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human C17orf75

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Handhabung

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    C17orf75 (Chromosome 17 Open Reading Frame 75 (C17orf75))

    Andere Bezeichnung

    C17orf75

    Hintergrund

    Synonyms: Njmu R1, Protein kinase Njmu R1, Protein Njmu R1, NJMU_HUMAN.

    Background: C17orf75 is a 396 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

    Gen-ID

    64149

    UniProt

    Q9HAS0
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