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TRIM50 Antikörper (HRP)

TRIM50 Reaktivität: Human, Ratte, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1419004
  • Target Alle TRIM50 Antikörper anzeigen
    TRIM50 (Tripartite Motif Containing 50 (TRIM50))
    Reaktivität
    • 33
    • 16
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 33
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRIM50 Antikörper ist konjugiert mit HRP
    Applikation
    • 32
    • 13
    • 13
    • 13
    • 12
    • 5
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TRIM50
    Isotyp
    IgG
    Top Product
    Discover our top product TRIM50 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TRIM50 (Tripartite Motif Containing 50 (TRIM50))
    Andere Bezeichnung
    TRIM50 (TRIM50 Produkte)
    Synonyme
    TRIM50A antikoerper, tripartite motif containing 50 antikoerper, tripartite motif-containing 50 antikoerper, TRIM50 antikoerper, Trim50 antikoerper
    Hintergrund

    Synonyms: E3 ubiquitin ligase, E3 ubiquitin protein ligase TRIM50, TRIM50A, Tripartite mot containing protein 50, tripartite mot protein 50A, tripartite mot-containing 50A, TRI50_HUMAN.

    Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM50 (tripartite motif containing 50), also known as TRIM50A or E3 ubiquitin-protein ligase TRIM50, is a 487 amino acid cytoplasmic protein that functions as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger, a B30.2/SPRY domain and a single B box-type zinc finger, TRIM50 belongs to the TRIM/RBCC family and undergoes post-translational auto-ubiquitination. TRIM50 exists as two alternatively spliced isoforms, designated TRIM50 alpha and TRIM50 beta, and has the ability to form dimers and trimers. The gene encoding TRIM50 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

    Gen-ID
    135892
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