ANKS1B Antikörper (Cy3)

Produktnummer ABIN1418687

Der Kaninchen-Polyklonal Anti-ANKS1B-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet zum Nachweis von ANKS1B in Proben aus Human, Maus und Ratte. }

Kurzübersicht für ANKS1B Antikörper (Cy3) (ABIN1418687)

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKS1B Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ANKS1B Antikörper (Cy3)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKS1B/AIDA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ANKS1B

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Andere Bezeichnung: ANKS1B

Hintergrund:

Synonyms: AIDA 1, AIDA-1, Amyloid-beta protein intracellular domain-associated protein 1, Anks1b, Ankyrin repeat and sterile alpha mot domain-containing protein 1B, ANS1B_HUMAN, E2A-PBX1-associated protein, EB-1.

Background: The _-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer?s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.

Gen-ID: 56899

UniProt: Q7Z6G8