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CINP Antikörper (Cy3)

Der Kaninchen Polyklonal Anti-CINP-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, CINP in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN1418573

Kurzübersicht für CINP Antikörper (Cy3) (ABIN1418573)

Target

Alle CINP Antikörper anzeigen
CINP

Reaktivität

  • 29
  • 16
  • 14
  • 1
Human, Maus, Ratte

Wirt

  • 27
  • 3
Kaninchen

Klonalität

  • 29
  • 1
Polyklonal

Konjugat

  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CINP Antikörper ist konjugiert mit Cy3

Applikation

  • 19
  • 12
  • 6
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CINP

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CINP

    Andere Bezeichnung

    CINP

    Hintergrund

    Synonyms: CINP protein, CDK2-interacting protein, CINP, CINP_HUMAN, Cyclin dependent kinase 2 interacting protein, Cyclin-dependent kinase 2-interacting protein, MGC849.

    Background: Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Specifically, Cdk2 interacts with Cyclins A, B1, B3, D, or E to control cell cycle progression. The Cyclin-dependent kinase 2-interacting protein (CINP) interacts with components of the replication complex and Cdk2 and Cdc7, thereby providing a functional and physical link between Cdk2 and Cdc7 during firing of the origins of replication. However, CINP is phopshorylated by Cdc7, but not by Cdk2. CINP also interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress and G2 checkpoint integrity.

    Gen-ID

    51550
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