FGFR1OP2 Antikörper (AA 51-150) (Cy7)

Produktnummer ABIN1416416

Der Kaninchen Polyklonal Anti-FGFR1OP2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, FGFR1OP2 in Proben von Human zu detektieren.

Kurzübersicht für FGFR1OP2 Antikörper (AA 51-150) (Cy7) (ABIN1416416)

Target: FGFR1OP2 (FGFR1 Oncogene Partner 2 (FGFR1OP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFR1OP2 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-FGFR1OP2 Antikörper (Cy7)

Bindungsspezifität: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FGFR1OP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FGFR1OP2

Target: FGFR1OP2 (FGFR1 Oncogene Partner 2 (FGFR1OP2))

Andere Bezeichnung: FGFR1OP2

Hintergrund:

Synonyms: DKFZp564O1863, FGFR1 oncogene partner 2, HSPC123, HSPC123 like, FGOP2_HUMAN.

Background: FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12,8)(p11,p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.

Gen-ID: 26127