DHX32 Antikörper (AA 561-660) (HRP)

Produktnummer ABIN1415493

Dieses Anti-DHX32-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DHX32 in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Ratte.

Kurzübersicht für DHX32 Antikörper (AA 561-660) (HRP) (ABIN1415493)

Target: DHX32 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 32 (DHX32))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX32 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DHX32 Antikörper (HRP)

Bindungsspezifität: AA 561-660

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHX32

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DHX32

Target: DHX32 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 32 (DHX32))

Andere Bezeichnung: DHX32

Hintergrund:

Synonyms: Ddx32, DEAD/H Asp-Glu-Ala-Asp/His box polypeptide 32, DEAD/H box 32, DEAD/H helicase like protein 1, DEAH Asp-Glu-Ala-His box polypeptide 32, DEAH box protein 32, DHLP1, DHX32, Helicase DDX32, HuDDX32, Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32, DHX32_HUMAN.

Background: DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX32 is a 743 amino acid nuclear protein that localizes to the mitochondria and is a member of the DEAD box helicase family. Expressed in various tissues, DDX32 is up-regulated by ionomycin in T lymphocytes and down-regulated in acute lymphoblastic leukemia. Considered a novel RNA helicase, DDX32 may play an important role in the development of colorectal cancer and may be involved in regulating T-cell response to certain apoptotic stimuli.