GRM2 Antikörper (Cy5.5)

Produktnummer ABIN1414422

Dieses Anti-GRM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GRM2 in IF (p). Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund und Huhn.

Kurzübersicht für GRM2 Antikörper (Cy5.5) (ABIN1414422)

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRM2 Antikörper ist konjugiert mit Cy5.5

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GRM2 Antikörper (Cy5.5)

Kreuzreaktivität: Huhn, Rind (Kuh), Hund, Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRM2/GLUR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Andere Bezeichnung: Metabotropic Glutamate Receptor 2

Hintergrund:

Synonyms: Glutamate Receptor Metabotropic 2, Gprc1b, AMPA selective glutamate receptor 2, GLUR 2, GLUR2, GLURB, Glutamate receptor metabotropic 2, Metabotropic Glutamate Receptor 2, GPRC1B, GRM 2, Grm2, mGlu 2, MGlu2, MGLUR 2, Mglur2, GRM2_HUMAN.

Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Molekulargewicht: 96kDa

Gen-ID: 2912

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport