ZNF281 Antikörper (AA 802-895) (HRP)

Produktnummer ABIN1413686

Der Kaninchen Polyklonal Anti-ZNF281-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ZNF281 in Proben von Human zu detektieren.

Kurzübersicht für ZNF281 Antikörper (AA 802-895) (HRP) (ABIN1413686)

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF281 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ZNF281 Antikörper (HRP)

Bindungsspezifität: AA 802-895

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF281

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ZNF281

Target: ZNF281 (Zinc Finger Protein 281 (ZNF281))

Andere Bezeichnung: ZNF281

Hintergrund:

Synonyms: Zfp281, GC box binding zinc finger protein 1, GC-box-binding zinc finger protein 1, GZP1, Transcription factor ZBP-99, ZBP 99, ZBP99, zfp281, Zinc finger DNA binding protein 99, Zinc finger DNA-binding protein 99, Zinc Finger Protein 281, ZN281_HUMAN, ZNF281, ZNP 99, ZNP 99 transcription factor, ZNP99.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Kr_ppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.

Gen-ID: 23528

Pathways: Embryonic Body Morphogenesis