DDX3X Antikörper (AA 2-100) (Cy5.5)

Produktnummer ABIN1413569

Der Kaninchen Polyklonal Anti-DDX3X-Antikörper wurde für IF (p) und IF (cc) validiert. Er ist geeignet, DDX3X in Proben von Human zu detektieren.

Kurzübersicht für DDX3X Antikörper (AA 2-100) (Cy5.5) (ABIN1413569)

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX3X Antikörper ist konjugiert mit Cy5.5

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-DDX3X Antikörper (Cy5.5)

Bindungsspezifität: AA 2-100

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DDX3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DDX3X

Target: DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))

Andere Bezeichnung: DDX3

Hintergrund:

Synonyms: ATP dependent RNA helicase DDX3X, ATP-dependent RNA helicase DDX3X, CAP Rf, DBX, DDX14, DDX3X, DDX3X_HUMAN, DEAD Asp Glu Ala Asp box polypeptide 3 X linked, DEAD box, DEAD box protein 3, DEAD box protein 3 X-chromosomal, DEAD box X isoform, DEAD/H Asp Glu Ala Asp/His box polypeptide 3, DEAD/H box 3, Fibroblast Growth Factor Inducible 14, Fin14, Helicase like protein 2, Helicase-like protein 2, HLP2, X isoform, X-chromosomal.

Background: DDX3 is involved in RNA metabolism. Two DDX3 paralogs are found in humans, DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections.

Gen-ID: 1654

Pathways: Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly