STRN4 Antikörper (AA 85-190) (Cy5)

Produktnummer ABIN1413262

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STRN4 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für STRN4 Antikörper (AA 85-190) (Cy5) (ABIN1413262)

Target: STRN4 (Striatin, Calmodulin Binding Protein 4 (STRN4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRN4 Antikörper ist konjugiert mit Cy5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-STRN4 Antikörper (Cy5)

Bindungsspezifität: AA 85-190

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Striatin 4/zinedin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu STRN4

Target: STRN4 (Striatin, Calmodulin Binding Protein 4 (STRN4))

Andere Bezeichnung: Striatin 4/zinedin

Hintergrund:

Synonyms: Striatin-4, STRN4, STRN4_HUMAN, ZIN, Zinedin.

Background: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD-repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somatodendritic compartment, including spines, subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.