STRN3 Antikörper (AA 75-180) (Cy3)

Produktnummer ABIN1413255

Dieses Anti-STRN3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von STRN3 in IF (cc) und IF (p). Geeignet für Maus.

Kurzübersicht für STRN3 Antikörper (AA 75-180) (Cy3) (ABIN1413255)

Target: STRN3 (Striatin, Calmodulin Binding Protein 3 (STRN3))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRN3 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-STRN3 Antikörper (Cy3)

Bindungsspezifität: AA 75-180

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Striatin 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu STRN3

Target: STRN3 (Striatin, Calmodulin Binding Protein 3 (STRN3))

Andere Bezeichnung: Striatin 3/SG2NA

Hintergrund:

Synonyms: Striatin3, Striatin-3, Cell cycle autoantigen SG2NA, Cell cycle S/G2 nuclear autoantigen, GS2NA, nuclear autoantigen, S/G2 antigen, SG2NA, Striatin 3, Striatin, calmodulin binding protein 3, STRN3_HUMAN.

Background: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling