HMX2 Antikörper (AA 122-200) (Cy7)

Produktnummer ABIN1411602

Dieses Anti-HMX2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HMX2 in IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für HMX2 Antikörper (AA 122-200) (Cy7) (ABIN1411602)

Target: HMX2 (H6 Family Homeobox 2 (HMX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMX2 Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-HMX2 Antikörper (Cy7)

Bindungsspezifität: AA 122-200

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HMX2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HMX2

Target: HMX2 (H6 Family Homeobox 2 (HMX2))

Andere Bezeichnung: HMX2

Hintergrund:

Synonyms: H6 family homeo box 2, H6 family homeobox 2, H6 homeo box 2, H6L, HMX 2, HMX2 , HMX2_HUMAN , Homeo box H6 family 2, Homeo box protein H6 family member 2, Homeobox H6 family 2 , Homeobox protein H6 family member 2, Homeobox protein HMX2, Nkx5 2.

Background: The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. HMX2 (H6 family homeobox 2), also known as H6L or Nkx5-2, is a 273 amino acid nuclear protein that belongs to the HMX homeobox family and contains one homeobox DNA-binding domain. HMX2 functions as a transcription factor that assists in specification of neuronal cell types and is essential for proper development of hypothalamus and inner ear. Hemizygous deletions of the gene encoding HMX2 are thought to lead to vestibular dysfunction, inner ear malformations and congenital sensorineural hearing loss.