AFF2 Antikörper (AA 1-80) (HRP)

Produktnummer ABIN1410734

Der Kaninchen Polyklonal Anti-AFF2-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, AFF2 in Proben von Human zu detektieren.

Kurzübersicht für AFF2 Antikörper (AA 1-80) (HRP) (ABIN1410734)

Target: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFF2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AFF2 Antikörper (HRP)

Bindungsspezifität: AA 1-80

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AFF2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu AFF2

Target: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Andere Bezeichnung: FMR2/AFF2

Hintergrund:

Synonyms: AF4/FMR2 family member 2, AF4/FMR2 family, member 2, AFF2, AFF2_HUMAN, FMR2, FMR2P, Fragile X E mental retardation syndrome protein, fragile X mental retardation 2, Fragile X mental retardation 2 protein, fragile X mental retardation gene associated with FRAXE, FRAXE, mild or borderline mental retardation, MRX2, OX19, Protein FMR-2, Protein Ox19.

Background: FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family. Expressed in the brain, placenta and lung, FMR2 exists as two isoforms produced by alternative splicing. Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, an X-linked form of mental retardation. Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, compared to six to thirty-five copies of the GCC repeat in a normal individual. It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site.