RNF146 Antikörper (AA 95-160) (Cy7)

Produktnummer ABIN1410528

Dieses Anti-RNF146-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RNF146 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für RNF146 Antikörper (AA 95-160) (Cy7) (ABIN1410528)

Target: RNF146 (Ring Finger Protein 146 (RNF146))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF146 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-RNF146 Antikörper (Cy7)

Bindungsspezifität: AA 95-160

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF146

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RNF146

Target: RNF146 (Ring Finger Protein 146 (RNF146))

Andere Bezeichnung: RNF146

Hintergrund:

Synonyms: Dactylidin, dJ351K20.1, DKFZP434O1427, E3 ubiquitin-protein ligase rnf146, RING finger protein 146, RN146_HUMAN, RNF 146, Rnf146, RP3 351K20.1.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF146 (RING finger protein 146), also known as Dactylidin, is a 359 amino acid protein that contains one RING-type zinc finger and one WWE domain. Via its RING-type zinc finger, RNF146 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF146 are associated with Alzheimer's disease (AD) and may lead to a higher risk of breast cancer. Two isoforms of RNF146 exist due to alternative splicing events.