BPTF Antikörper (AA 2801-3046) (HRP)

Produktnummer ABIN1410368

Der Kaninchen Polyklonal anti-BPTF Antikörper wird verwendet zum Nachweis von BPTF in Proben von Human. Er wurde validiert für WB, IHC (p) und IHC (fro).

Kurzübersicht für BPTF Antikörper (AA 2801-3046) (HRP) (ABIN1410368)

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BPTF Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-BPTF Antikörper (HRP)

Bindungsspezifität: AA 2801-3046

Verwendungszweck: BPTF Polyclonal Antibody, HRP Conjugated

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Chicken,Rabbit,GuineaPig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BPTF/FALZ

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BPTF

Target: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Andere Bezeichnung: BPTF/FALZ

Hintergrund:

Synonyms: Bromodomain and PHD finger containing transcription factor, Bromodomain PHD finger transcription factor, FAC 1, BPTF / FALZ, fac1, FALZ, Fetal Alz 50 clone 1 protein, Fetal Alz 50 reactive clone 1, Fetal Alzheimer antigen, Nucleosome remodeling factor, Nucleosome remodeling factor subunit BPTF, Nucleosome remodeling factor, large subunit, NURF 301, NURF301.

Background: BPTF is a 2,907 amino acid protein encoded by the human gene BPTF. BPTF belongs to the PBTF family and contains one bromodomain, one DDT domain and two PHD-type zinc fingers. BPTF acts as a histone-binding component of NURF (nucleosome-remodeling factor). The NURF complex, which consists of SMARCA1, BPTF, RbAp46 and RbAp48, acts to catalyze ATP-dependent nucleosome sliding and facilitates transcription of chromatin. It specifically recognizes histone H3 tails trimethylated on 'Lys-4' (H3-K4Me3), which mark transcription start sites of virtually all active genes. BPTF may also help regulate transcription through direct binding to DNA or transcription factors.