TAS2R16 Antikörper (Cy3)

Produktnummer ABIN1410219

Dieses Anti-TAS2R16-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TAS2R16 in WB. Geeignet für Human.

Kurzübersicht für TAS2R16 Antikörper (Cy3) (ABIN1410219)

Target: TAS2R16 (Taste Receptor, Type 2, Member 16 (TAS2R16))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAS2R16 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB)

Produktdetails anti-TAS2R16 Antikörper (Cy3)

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TAS2R16

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TAS2R16

Target: TAS2R16 (Taste Receptor, Type 2, Member 16 (TAS2R16))

Andere Bezeichnung: Tas2r16

Hintergrund:

Synonyms: TAS2R-16, T2R16, Taste receptor type 2 member 16, T2R16_HUMAN.

Background: T2R16 is a 291 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. Acting in the oral cavity and the gastrointestinal tract, T2R16 is a gustducin-coupled receptor that is implicated in the perception of bitter compounds. T2R16 mediates responses to certain taste through PLC 2, a phospholipase C selectively expressed in taste tissue, and the calcium-regulated cation channel TRPM5. Expressed in a subset of gustducin-positive taste receptor cells of the tongue and epithelia, T2R16 confers bitter perception of salicin to non-taster mice. The gene that encodes T2R16 consists of 996 bases and maps to human chromosome 7q31. Chromosome 7 houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The Lys-172 polymorphism in T2R16 is associated with genetic susceptibility to alcoholism.