PDE7A Antikörper (HRP)

Produktnummer ABIN1409978

Der Kaninchen Polyklonal Anti-PDE7A-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, PDE7A in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für PDE7A Antikörper (HRP) (ABIN1409978)

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE7A Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PDE7A Antikörper (HRP)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDE7A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), IHC-P(1:100-500)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % Gentamicin.

Konservierungsmittel: Gentamicin sulfate

Vorsichtsmaßnahmen: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu PDE7A

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Andere Bezeichnung: Pde7a

Hintergrund:

Phosphodiesterases (PDE, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular tissue and adipose tissue, respectively. PDE3A, is found in myocardium and platelets and PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.

Synonyms: HCP 1, HCP1, High affinity cAMP specic 3'5' cyclic phosphodiesterase 7A, High affinity cAMP-specic 3'', P2A, PDE 7, PDE 7A, PDE7, PDE71, PDE7A, PDE7A_HUMAN, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, Phosphodiesterase7A, Rolipram insensitive phosphodiesterase type 7, TM 22, TM22, 5''-cyclic phosphodiesterase 7A.

Pathways: cAMP Metabolic Process